SCHEMBL669434

SCHEMBL669434

NC(C(=O)c1ccccc1)(C(=O)c1ccccc1)C(N)(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 7/20 0.58
TDP1 Q9NUW8 4/20 0.52
TSHR P16473 2/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
HSD17B10 Q99714 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CYP2C19 P33261 2/20 0.52
POLB P06746 1/20 0.52
PARP1 P09874 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
CES2 O00748 4/20 0.50
ALDH1A1 P00352 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
SRC P12931 1/20 0.47
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14645923 0.82 CES1 (0.56) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL3134419 0.80 CES1 (0.60) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL9632467 0.80 CES1 (0.54) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL1878464 0.78 CES1 (0.52) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL27879678 0.78 CES1 (0.52) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL27914495 0.78 MAPT (0.52) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL1799477 0.78 CES1 (0.64) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL27938670 0.78 CES1 (0.64) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL29067111 0.77 CES1 (0.50) CES1TDP1TSHRCYP3A4MAPT
SCHEMBL461653 0.77 CES1 (0.50) CES1TDP1TSHRCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 546 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2606175-B1 METHOD FOR REMOVING HEXENURONIC ACIDS ÅBO AKADEMI UNIVERSITY (FI) 2016-04-20 EP claimed
EP-2606175-B1 METHOD FOR REMOVING HEXENURONIC ACIDS ÅBO AKADEMI UNIVERSITY (FI) 2016-04-20 EP disclosed
EP-2606175-A1 METHOD FOR REMOVING HEXENURONIC ACIDS Åbo Akademi University (FI) 2013-06-26 EP disclosed
WO-2012022840-A1 METHOD FOR REMOVING HEXENURONIC ACIDS ÅBO AKADEMI UNIVERSITY (FI) 2012-02-23 WO disclosed
US-7615524-B2 Multicompartments containing laundering additives; fabric softener THE PROCTER & GAMBLE CO. (US) 2009-11-10 US disclosed
EP-1113071-B1 Detergent compositions PROCTER & GAMBLE (US) 2008-07-09 EP disclosed
US-20080113893-A1 Process for preparing detergent tablet ROWLAND BARRY 2008-05-15 US disclosed
US-7351683-B2 Laundry additive sachet THE PROCTER & GAMBLE COMPANY (US) 2008-04-01 US disclosed
EP-1165732-B1 FABRIC SOFTENING COMPONENT PROCTER & GAMBLE (US) 2008-02-13 EP disclosed
US-7320955-B2 Compositions comprising complexes of cyclodextrin and at least one laundry treatment active THE PROCTER & GAMBLE COMPANY (US) 2008-01-22 US disclosed
WO-1995028465-A1 DETERGENTS CONTAINING A BUILDER AND A DELAYED RELEASE PEROXYACID BLEACH SOURCE THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
WO-1995028464-A1 DETERGENTS CONTAINING A HEAVY METAL SEQUESTRANT AND A DELAYED RELEASE PEROXYACID BLEACH SYSTEM THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
WO-1995028466-A1 DETERGENTS CONTAINING A SURFACTANT AND A DELAYED RELEASE ENZYME THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
WO-1995028454-A1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
WO-1995028469-A1 DETERGENTS CONTAINING A BUILDER AND A DELAYED RELEASE ENZYME THE PROCTER & GAMBLE COMPANY (US) 1995-10-26 WO disclosed
EP-0672749-A1 Bleaching compositions THE PROCTER & GAMBLE COMPANY (US) 1995-09-20 EP disclosed
WO-1995018206-A1 PEROXYACID BLEACH PRECURSOR PARTICLE COATED WITH A WATER SOLUBLE ORGANIC ACID IN PARTICULATE FORM THE PROCTER & GAMBLE COMPANY (US) 1995-07-06 WO disclosed
EP-0659876-A2 Detergent additive composition. THE PROCTER & GAMBLE COMPANY (US) 1995-06-28 EP disclosed
WO-1995012652-A1 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-05-11 WO disclosed
WO-1995001416-A1 MACHINE DISHWASHING COMPOSITION CONTAINING OXYGEN BLEACH AND PARAFFIN OIL AND BENZOTRIAZOLE COMPOUND SILVER TARNISHING INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO disclosed