Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 7/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134419 | 0.86 | CES1 (0.60) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL27638715 | 0.82 | CES1 (0.50) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL8506425 | 0.82 | CES1 (0.50) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL10887738 | 0.80 | CES1 (0.53) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL4618681 | 0.80 | CES1 (0.58) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL21109870 | 0.80 | CES1 (0.58) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL669434 | 0.80 | CES1 (0.58) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL226691 | 0.80 | CES1 (0.58) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL10493250 | 0.79 | CYP1A2 (0.48) | CES1SRCTSHRTDP1MAPT | |
| SCHEMBL9076470 | 0.79 | CES1 (0.47) | CES1SRCTSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368903-B1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE) | AlliedSignal Inc. (US) | 1992-08-26 | — | — | EP | disclosed |
| EP-0368903-A1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE). | ALLIED SIGNAL INC (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0325247-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-07-26 | — | — | EP | disclosed |
| WO-1989000171-A1 | ALTERNATING ALIPHATIC-AROMATIC POLY(ESTERAMIDE) | ALLIED-SIGNAL INC. (US) | 1989-01-12 | — | — | WO | disclosed |
| US-4767839-A | LIQUID CRYSTAL-FROM A DIACID AND DIESTERDIAMINE | ALLIED-SIGNAL INC. (US) | 1988-08-30 | — | — | US | disclosed |