Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3248704 | 0.86 | CYP1A2 (0.50) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL472008 | 0.86 | CYP1A2 (0.50) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL27516881 | 0.77 | ATM (0.49) | NPC1RAB9AMEN1KMT2ACA12 | |
| SCHEMBL7452871 | 0.74 | CYP1A2 (0.47) | ACENPC1RAB9A | |
| SCHEMBL7452874 | 0.74 | CYP1A2 (0.47) | ACENPC1RAB9A | |
| Tyrosine SCHEMBL2672368 | 0.73 | SLC7A5 (0.61) | — | |
| SCHEMBL8986800 | 0.72 | NPC1 (0.62) | NPC1RAB9A | |
| SCHEMBL8986798 | 0.72 | NPC1 (0.62) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11798527 | 0.70 | NPC1 (0.61) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11798523 | 0.70 | NPC1 (0.61) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116538-A1 | RESPIRATORY SYNCYTIAL VIRUS (RSV) REPLICATION INHIBITORS | Fondation The Ark (CH) | 2017-01-18 | — | — | EP | disclosed |
| WO-2017004672-A1 | PEPTIDYL TPOR ANTAGONISTS AND USES THEREOF | POLYMERS CRC LIMITED (AU) | 2017-01-12 | — | — | WO | disclosed |
| WO-2015135925-A1 | RESPIRATORY SYNCYTIAL VIRUS (RSV) REPLICATION INHIBITORS | FONDATION THE ARK (CH) | 2015-09-17 | — | — | WO | disclosed |
| WO-2004099238-A1 | NOVEL mu-CONOTOXIN PEPTIDES | THE UNIVERSITY OF QUEENSLAND (AU) | 2004-11-18 | — | — | WO | disclosed |