Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA3 | P15088 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7452874 | 1.00 | CYP1A2 (0.47) | CYP1A2ACECPA3FOLH1SRR | |
| SCHEMBL472008 | 0.83 | CYP1A2 (0.50) | CYP1A2CPA3FOLH1SRRNPC1 | |
| SCHEMBL3248704 | 0.83 | CYP1A2 (0.50) | CYP1A2CPA3FOLH1SRRNPC1 | |
| Hydrochloric Acid SCHEMBL11438414 | 0.79 | ALPI (0.47) | CYP1A2CPA3FOLH1SRRALPI | |
| SCHEMBL7266285 | 0.77 | CYP1A2 (0.52) | CYP1A2CPA3FOLH1NPC1RAB9A | |
| SCHEMBL22384110 | 0.77 | CYP1A2 (0.52) | CYP1A2CPA3FOLH1NPC1RAB9A | |
| SCHEMBL28146093 | 0.77 | CYP1A2 (0.52) | CYP1A2CPA3FOLH1SRRALPI | |
| SCHEMBL121727 | 0.77 | MAPT (0.61) | CYP1A2CPA3FOLH1SRRALPI | |
| SCHEMBL10482159 | 0.77 | CPA3 (0.58) | CYP1A2ACECPA3FOLH1SRR | |
| SCHEMBL121728 | 0.77 | MAPT (0.61) | CYP1A2CPA3FOLH1SRRALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950046-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (CA) | 1999-10-20 | — | — | EP | claimed |
| WO-1998012176-A1 | 3,4-DISUBSTITUTED AZETIDIN-2-ONE DERIVATIVES USEFUL AS CYSTEINE PROTEINASE REGULATORS | SYNPHAR LABORATORIES INC. (US) | 1998-03-26 | — | — | WO | claimed |