Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692044 | 0.84 | TSHR (0.50) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1697677 | 0.84 | KDM4E (0.82) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL1997708 | 0.83 | KMT2A (0.45) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL28697718 | 0.81 | L3MBTL1 (0.44) | KDM4EKMT2AMEN1RECQLALOX15 | |
| SCHEMBL22230490 | 0.80 | MRGPRX4 (0.44) | KDM4EKMT2AMEN1RECQLALDH1A1 | |
| SCHEMBL6445620 | 0.79 | KDM4E (0.68) | KDM4EKMT2AMEN1HSD17B10HPGD | |
| SCHEMBL7176813 | 0.79 | KDM4E (0.49) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL29905006 | 0.78 | KDM4E (0.55) | KDM4EKMT2AMEN1RECQLHSD17B10 | |
| SCHEMBL2592081 | 0.78 | L3MBTL1 (0.50) | KDM4EKMT2AMEN1HSD17B10MAPK1 | |
| SCHEMBL9312497 | 0.76 | KMT2A (0.59) | KDM4EKMT2AMEN1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |