Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.68 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.57 |
| ▸ | RAF1 | P04049 | 5/20 | 0.49 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | ARAF | P10398 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694585 | 1.00 | LRRK2 (0.68) | LRRK2PDPK1RAF1MAP1LC3BEGFR | |
| SCHEMBL5774062 | 0.85 | RAF1 (0.68) | LRRK2PDPK1RAF1MAP1LC3BEGFR | |
| SCHEMBL5774067 | 0.85 | RAF1 (0.68) | LRRK2PDPK1RAF1MAP1LC3BEGFR | |
| SCHEMBL6695402 | 0.85 | ERBB2 (0.67) | LRRK2PDPK1RAF1MAP1LC3BEGFR | |
| SCHEMBL6695400 | 0.85 | ERBB2 (0.67) | LRRK2PDPK1RAF1MAP1LC3BEGFR | |
| SCHEMBL6689420 | 0.81 | LRRK2 (1.00) | LRRK2RAF1EGFRPSEN1PSEN2 | |
| SCHEMBL6687017 | 0.81 | LRRK2 (0.73) | LRRK2RAF1MAP1LC3BEGFRPSEN1 | |
| SCHEMBL5476171 | 0.79 | RAF1 (0.71) | LRRK2PDPK1RAF1EGFRMAPT | |
| SCHEMBL5476173 | 0.79 | RAF1 (0.71) | LRRK2PDPK1RAF1EGFRMAPT | |
| SCHEMBL6692724 | 0.78 | RAF1 (0.46) | LRRK2PDPK1RAF1MAP1LC3BEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069998-A2 | OXINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2004-08-19 | — | — | WO | disclosed |