SCHEMBL6694623

SCHEMBL6694623

CC(C)(C)C(C)(O)C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 6/20 0.52
SRC P12931 1/20 0.52
TSHR P16473 4/20 0.44
CES2 O00748 4/20 0.44
ALDH1A1 P00352 2/20 0.44
DAO P14920 1/20 0.44
NAPRT Q6XQN6 1/20 0.44
TDP1 Q9NUW8 3/20 0.44
HSD17B10 Q99714 2/20 0.44
PDK1 Q15118 3/20 0.41
PDK2 Q15119 3/20 0.41
PDK3 Q15120 3/20 0.41
PDK4 Q16654 3/20 0.41
ABCC9 O60706 2/20 0.41
ABCC8 Q09428 2/20 0.41
KCNJ11 Q14654 2/20 0.41
KCNJ8 Q15842 2/20 0.41
ABCB11 O95342 1/20 0.41
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11341422 0.91 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL27479554 0.82 CES1 (0.52) CES1SRCTSHRCES2ALDH1A1
SCHEMBL1606581 0.81 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL21310 0.81 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL9105008 0.81 CES1 (0.56) CES1SRCTSHRCES2ALDH1A1
SCHEMBL9718709 0.79 CES1 (0.55) CES1SRCTSHRCES2ALDH1A1
Hydrogen Sulfide SCHEMBL11500168 0.79 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1
SCHEMBL11500171 0.79 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1
Bicarbonate SCHEMBL4881468 0.79 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1
SCHEMBL5704582 0.79 CES1 (0.54) CES1SRCTSHRCES2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040077744-A1 Irradiation polymerization of acrylamide and/or monomer blends in the presence of photoinintiators, to form water soluble polymers used as flocculants, flow control agents, coagulants, dispersants, superabsorbents or binders CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2004-04-22 US disclosed
EP-1368382-A1 POLYMERISATION PROCESS Ciba Specialty Chemicals Water Treatments Limited (GB) 2003-12-10 EP disclosed
WO-2002066520-A1 POLYMERISATION PROCESS CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2002-08-29 WO disclosed
US-4547394-A PHOTOINITIATORS FOR PHOTOPOLYMERIZATION MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-10-15 US disclosed