Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341422 | 0.83 | CES1 (0.56) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL50469 | 0.80 | CES1 (0.58) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL6694623 | 0.79 | CES1 (0.52) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL10090157 | 0.78 | CES1 (0.60) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL8332006 | 0.78 | CES1 (0.60) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL25114 | 0.78 | SRC (0.66) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL3661644 | 0.78 | CES1 (0.60) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL10324232 | 0.77 | CES1 (0.50) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL27980842 | 0.77 | CES1 (0.50) | CES1SRCTSHRTDP1ALDH1A1 | |
| SCHEMBL27794375 | 0.77 | CES1 (0.50) | CES1SRCTSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147901-A | PROPIONPHENONE DERIVATIVES AS PHOTOINITIATORS FOR PHOTOPOLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1992-09-15 | — | — | US | disclosed |
| US-4795766-A | OF ETHYLENICALLY UNSATURATED COMPOUNDS; PRINTING INK | CIBA-GEIGY CORPORATION (US) | 1989-01-03 | — | — | US | disclosed |