Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.74 |
| ▸ | CTSL | P07711 | 12/20 | 0.73 |
| ▸ | CTSK | P43235 | 4/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364143 | 0.85 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5364153 | 0.85 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5360161 | 0.85 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5360158 | 0.85 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5356673 | 0.80 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5356678 | 0.80 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5372153 | 0.78 | CTSS (0.85) | CTSSCTSLCTSK | |
| SCHEMBL5372151 | 0.78 | CTSS (0.85) | CTSSCTSLCTSK | |
| SCHEMBL5358217 | 0.76 | CTSS (1.00) | CTSSCTSLCTSK | |
| SCHEMBL5358220 | 0.76 | CTSS (1.00) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004112709-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-12-29 | — | — | WO | claimed |
| WO-2004112709-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-12-29 | — | — | WO | disclosed |