Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31569428 | 0.82 | ATR (0.45) | PKML3MBTL1TDP1ATRMAP2K1 | |
| SCHEMBL29907674 | 0.79 | ATR (0.50) | PKML3MBTL1TDP1ATRMAP2K1 | |
| SCHEMBL16790455 | 0.79 | ATR (0.50) | PKML3MBTL1TDP1ATRMAP2K1 | |
| SCHEMBL17714455 | 0.79 | TDP1 (0.50) | PKML3MBTL1TDP1MAP2K1KDM4E | |
| SCHEMBL21957938 | 0.79 | TDP1 (0.50) | PKML3MBTL1TDP1MAP2K1KDM4E | |
| SCHEMBL29056995 | 0.78 | ALDH1A1 (0.66) | KDM4EALDH1A1LMNAHTTPOLB | |
| Hydrochloric Acid SCHEMBL21957930 | 0.77 | TDP1 (0.49) | PKML3MBTL1TDP1MAP2K1KDM4E | |
| SCHEMBL2732104 | 0.77 | TDP1 (0.49) | PKML3MBTL1TDP1MAP2K1KDM4E | |
| SCHEMBL27497541 | 0.77 | TDP1 (0.49) | PKML3MBTL1TDP1MAP2K1KDM4E | |
| SCHEMBL6017355 | 0.77 | TDP1 (0.54) | PKML3MBTL1TDP1MAP2K1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024419-A2 | BRADYKININ RECEPTOR AGONISTS AND USES THEREOF TO TREAT OCULAR HYPERTENSION AND GLAUCOMA | ALCON RESEARCH, LTD. (US) | 2012-02-23 | — | — | WO | disclosed |