Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690929 | 0.92 | LMNA (0.40) | LMNAALDH1A1L3MBTL1GAATSHR | |
| SCHEMBL6690282 | 0.91 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1L3MBTL1GAA | |
| SCHEMBL6693776 | 0.88 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1L3MBTL1GAA | |
| SCHEMBL6694186 | 0.87 | MPI (0.38) | SMN1; SMN2LMNAALDH1A1GAATSHR | |
| SCHEMBL6690604 | 0.84 | LMNA (0.39) | LMNAALDH1A1L3MBTL1GAATSHR | |
| SCHEMBL6692038 | 0.79 | SMN1; SMN2 (0.38) | SMN1; SMN2LMNAALDH1A1L3MBTL1GAA | |
| SCHEMBL6693731 | 0.78 | KMT2A (0.37) | LMNAALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL6697961 | 0.77 | MPI (0.38) | SMN1; SMN2ALDH1A1GAATSHRMAPT | |
| SCHEMBL6689067 | 0.77 | HRH3 (0.35) | SMN1; SMN2LMNAALDH1A1L3MBTL1TSHR | |
| SCHEMBL6693788 | 0.76 | MEN1 (0.35) | LMNAALDH1A1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |