⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38378 | 0.81 | LMNA (0.34) | — | |
| SCHEMBL9008183 | 0.79 | — | — | |
| SCHEMBL21408611 | 0.79 | — | — | |
| SCHEMBL3385951 | 0.79 | — | — | |
| SCHEMBL83544 | 0.77 | — | — | |
| SCHEMBL7516446 | 0.77 | — | — | |
| SCHEMBL429701 | 0.77 | — | — | |
| SCHEMBL16280840 | 0.77 | — | — | |
| SCHEMBL13900281 | 0.77 | — | — | |
| SCHEMBL3097066 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040009973-A1 | Phenylenediamine derivatives N-substituted with benzyl- or heteroarylmethyl- groups | 4SC AG (DE) | 2004-01-15 | — | — | US | disclosed |
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |
| WO-2003074047-A1 | INDOLE DERIVATIVES AS MODULATORS OF POTASSIUM CHANNELS | 4SC AG (DE) | 2003-09-12 | — | — | WO | disclosed |