Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151371 | 0.89 | ALDH1A1 (0.33) | ALDH1A1MAPK1HTT | |
| SCHEMBL6693760 | 0.83 | MEN1 (0.40) | ALDH1A1HTTNPC1RAB9A | |
| SCHEMBL6848981 | 0.82 | PARP15 (0.33) | ALDH1A1MAPK1HTT | |
| SCHEMBL6695155 | 0.82 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL3255597 | 0.81 | NPC1 (0.35) | TRPM8ALDH1A1MAPK1HTTNPC1 | |
| SCHEMBL5604918 | 0.81 | MEN1 (0.32) | ALDH1A1MAPK1HTT | |
| SCHEMBL6426491 | 0.80 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL6151821 | 0.80 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL3255428 | 0.79 | NPC1 (0.44) | TRPM8ALDH1A1NPC1RAB9A | |
| SCHEMBL12345808 | 0.79 | ALDH1A1 (0.33) | TRPM8ALDH1A1MAPK1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774086-B2 | HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2004-08-10 | — | — | US | disclosed |
| US-20030191027-A1 | 3-Aminocarbonyl-substituted benzoylcyclohexanediones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191027-A1 | 3-Aminocarbonyl-substituted benzoylcyclohexanediones | CYP1B1, CBR3, CBR1 | TRPM8 4329/4885ALDH1A1 255/4885MAPK1 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.