Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.40 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4947883 | 0.97 | FDPS (0.42) | FDPSMETAP1TSHRCA12CA1 | |
| SCHEMBL1982866 | 0.97 | FDPS (0.42) | FDPSMETAP1TSHRCA12CA1 | |
| SCHEMBL1781953 | 0.94 | FDPS (0.40) | FDPSMETAP1TSHRCA12CA1 | |
| SCHEMBL346744 | 0.94 | FDPS (0.40) | FDPSMETAP1TSHRCA12CA1 | |
| SCHEMBL4463562 | 0.94 | FDPS (0.40) | FDPSMETAP1TSHRCA12CA1 | |
| SCHEMBL11752360 | 0.94 | FDPS (0.40) | FDPSMETAP1TSHRCA12CA1 | |
| SCHEMBL29181912 | 0.94 | FDPS (0.40) | FDPSMETAP1TSHRCA12CA1 | |
| SCHEMBL4466868 | 0.94 | FDPS (0.40) | FDPSMETAP1TSHRCA12CA1 | |
| Hydrogen Sulfide SCHEMBL6903091 | 0.94 | TSHR (0.43) | FDPSMETAP1TSHRCA12CA1 | |
| SCHEMBL8811717 | 0.81 | FDPS (0.46) | FDPSLPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0945488-A2 | Rubber composition | Bridgestone Corporation (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5939493-A | NATURAL RUBBER OR DIENE SYNTHETIC RUBBER, METAL DITHIOPHOSPHATE, TERTIARY AMINE; REINFORCING INORGANIC FILLER | BRIDGESTONE CORPORATION (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |
| EP-0864604-A2 | Rubber composition | Bridgestone Corporation (JP) | 1998-09-16 | — | — | EP | disclosed |