Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.52 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25226487 | 0.98 | GNAI3 (0.55) | GNAI3GNAO1GNAI1SOS1EPHX1 | |
| SCHEMBL8802474 | 0.86 | — | — | |
| SCHEMBL14376953 | 0.86 | GNAI3 (0.58) | GNAI3GNAO1GNAI1SOS1EPHX1 | |
| SCHEMBL12120418 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL7006416 | 0.85 | KCNH2 (0.55) | GNAI3GNAO1GNAI1SOS1EPHX1 | |
| SCHEMBL10814840 | 0.83 | GNAI3 (0.65) | GNAI3GNAO1GNAI1SOS1EPHX1 | |
| SCHEMBL12633896 | 0.83 | GNAI3 (0.65) | GNAI3GNAO1GNAI1SOS1EPHX1 | |
| SCHEMBL18045582 | 0.82 | SPHK1 (0.42) | GNAI3GNAO1GNAI1DPP7RAD52 | |
| SCHEMBL701060 | 0.82 | — | — | |
| SCHEMBL8682833 | 0.80 | GNAI3 (0.67) | GNAI3GNAO1GNAI1SOS1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250268919-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER | AMNEAL PHARMACEUTICALS LLC | 2025-08-28 | — | — | US | disclosed |
| CN-118871116-A | Compounds for the treatment of cancer | 卡希夫生物科学有限公司 | 2024-10-29 | — | — | CN | disclosed |
| EP-4444318-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER | Kashiv Biosciences, LLC (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023195773-A1 | HETEROARYL DERIVATIVE AND USE THEREOF | 보로노이 주식회사 | 2023-10-12 | — | — | WO | disclosed |
| WO-2023105303-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER | KASHIV BIOSCIENCES, LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023105303-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER | KASHIV BIOSCIENCES, LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| EP-3885344-A2 | PYRIMIDINE COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USES THEREOF | InventisBio Co., Ltd. (CN) | 2021-09-29 | — | — | EP | disclosed |
| US-11111233-B2 | Amino pyrimidine compound for inhibiting protein tyrosine kinase activity | SHENZHEN TARGETRX, INC. (CN) | 2021-09-07 | — | — | US | disclosed |
| EP-2699546-B1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENT & INDUSTRIAL RESEARCH ORGANISATION (AU) | 2019-06-26 | — | — | EP | disclosed |
| EP-2699546-B1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENT & INDUSTRIAL RESEARCH ORGANISATION (AU) | 2019-06-26 | — | — | EP | disclosed |
| US-9409122-B2 | Gas capture process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-08-09 | — | — | US | disclosed |
| US-9409122-B2 | Gas capture process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-08-09 | — | — | US | disclosed |
| US-9409122-B2 | Gas capture process | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-08-09 | — | — | US | disclosed |
| US-20140127103-A1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2014-05-08 | — | — | US | disclosed |
| US-20140127103-A1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2014-05-08 | — | — | US | disclosed |
| US-20140127103-A1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2014-05-08 | — | — | US | disclosed |
| EP-2699546-A1 | GAS CAPTURE PROCESS | Commonwealth Scientific & Industrial Research Organisation (AU) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012142668-A1 | GAS CAPTURE PROCESS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-10-26 | — | — | WO | disclosed |
| US-20120252815-A1 | INHIBITORS OF SPHINGOSINE KINASE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-10-04 | — | — | US | disclosed |
| US-20040186160-A1 | Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors | SUGEN, INC. | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250268919-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER | BRCA1, KLK3, BRDT | GNAI3 1458/4885GNAO1 2206/4885GNAI1 1597/4885 |
| US-20120252815-A1 | INHIBITORS OF SPHINGOSINE KINASE | SPHK1, S1PR3, SPHK2 | GNAI3 198/4885GNAO1 356/4885GNAI1 270/4885 |
| US-11111233-B2 | Amino pyrimidine compound for inhibiting protein tyrosine kinase activity | LCK, WEE1, JAK1 | GNAI3 1455/4885GNAO1 1230/4885GNAI1 607/4885 |
| US-20040186160-A1 | Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors | MAP3K15, MAP3K20, MAP3K19 | GNAI3 313/4885GNAO1 1008/4885GNAI1 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.