Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692844 | 0.76 | HTT (0.42) | MAPTHTTTSHRCYP3A4CA9 | |
| SCHEMBL6696687 | 0.74 | CYP1A2 (0.44) | MAPTTDP1TSHRCYP1A2CYP3A4 | |
| SCHEMBL6695376 | 0.71 | CA12 (0.39) | MAPTTDP1SMN1; SMN2HTTCYP1A2 | |
| SCHEMBL6694010 | 0.69 | TP53 (0.43) | SMN1; SMN2CYP1A2CYP3A4CYP2C19CA12 | |
| SCHEMBL3066536 | 0.68 | MAPT (0.36) | MAPTTDP1SMN1; SMN2TSHRCYP1A2 | |
| SCHEMBL660605 | 0.67 | MAPT (0.55) | MAPTTDP1ABCG2SMN1; SMN2CYP1A2 | |
| SCHEMBL28104077 | 0.67 | MAPT (0.46) | MAPTTDP1PLAUAOC3SMN1; SMN2 | |
| SCHEMBL16541046 | 0.67 | MAPT (0.42) | MAPTTDP1AOC3CYP1A2TUBB1 | |
| SCHEMBL30701949 | 0.66 | CA9 (0.50) | MAPTTDP1ABCG2AOC3SMN1; SMN2 | |
| SCHEMBL3674074 | 0.66 | CA9 (0.50) | MAPTTDP1ABCG2AOC3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3553083-B2 | — | — | 2004-08-11 | — | — | JP | claimed |
| EP-0852494-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-15 | — | — | EP | claimed |
| WO-1997009973-A2 | PERIPHERALLY ACTIVE ANTI-HYPERALGESIC OPIATES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-03-20 | — | — | WO | claimed |