Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | BLM | P54132 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681528 | 0.79 | MCL1 (0.46) | KDM4EGLAALDH1A1MCL1HPGD | |
| SCHEMBL6695728 | 0.78 | MCL1 (0.45) | KDM4EMEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL3667719 | 0.76 | HTT (0.49) | KDM4EMEN1KMT2AGLAALDH1A1 | |
| SCHEMBL3672345 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1MCL1HPGDGAA | |
| SCHEMBL2918049 | 0.76 | GRIA1 (0.47) | KDM4EMEN1KMT2AALDH1A1MCL1 | |
| Water SCHEMBL4777584 | 0.76 | GRIA1 (0.47) | KDM4EMEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL3676539 | 0.76 | MCL1 (0.43) | KDM4EMEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL3672706 | 0.75 | KDM4E (0.40) | KDM4EMEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL3666760 | 0.74 | MCL1 (0.41) | KDM4EMEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL31264118 | 0.74 | MEN1 (0.50) | KDM4EMEN1KMT2ABLMGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465626-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES | Eisai Co., Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003047577-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING DIHYDROPYRIDINONE COMPOUNDS AND AN IMMUNOREGULATORY OR AN ANTIINFLAMMATORY AGENT AND THEIR USES | EISAI CO LTD (JP) | 2003-06-12 | — | — | WO | disclosed |