Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL645565 | 0.82 | CA4 (0.35) | LMNAHIF1AKDM4ECYP2D6ALDH1A1 | |
| SCHEMBL301441 | 0.82 | CA4 (0.35) | LMNAHIF1AKDM4ECYP2D6ALDH1A1 | |
| SCHEMBL5423659 | 0.79 | CA4 (0.36) | LMNAHIF1AKDM4ECYP2D6ALDH1A1 | |
| SCHEMBL5414886 | 0.78 | CA4 (0.32) | — | |
| SCHEMBL5412474 | 0.78 | CA4 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL2244551 | 0.78 | SLC6A2 (0.32) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL6697038 | 0.78 | MAOA (0.37) | MAOAMAOBSLC6A2TAAR1SLC6A4 | |
| SCHEMBL5425583 | 0.77 | CA4 (0.31) | — | |
| SCHEMBL5420425 | 0.77 | CA4 (0.31) | — | |
| SCHEMBL5415001 | 0.77 | ESR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040197484-A1 | Coating liquid for forming insulating film and method for producing insulating film | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-10-07 | — | — | US | disclosed |
| US-5385961-A | Coating aminofunctional polysiloxane over solid phosphite core; nonhydrolyzing | GENERAL ELECTRIC COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0609034-A1 | Amino silicone/phosphite compositions | GENERAL ELECTRIC COMPANY (US) | 1994-08-03 | — | — | EP | disclosed |
| US-4496705-A | TREATING POLYSILOXANE WITH ORGANO-SULTONE | GENERAL ELECTRIC COMPANY (US) | 1985-01-29 | — | — | US | disclosed |