Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5002926 | 0.83 | GABRA1 (0.41) | CYP1A2CYP3A4LMNAHIF1ACA1 | |
| SCHEMBL9119712 | 0.79 | TSHR (0.32) | ALDH1A1 | |
| SCHEMBL6697047 | 0.79 | CYP2D6 (0.35) | CYP2D6CYP1A2CYP3A4NFKB1PNMT | |
| SCHEMBL4999824 | 0.77 | TSHR (0.50) | ALDH1A1KDM4E | |
| SCHEMBL6702147 | 0.77 | CYP1A2 (0.33) | CYP2D6CYP1A2CYP3A4NFKB1PNMT | |
| SCHEMBL9148449 | 0.75 | CA1 (0.38) | CYP2D6CYP1A2CYP3A4LMNAALDH1A1 | |
| SCHEMBL14395925 | 0.72 | CYP2D6 (0.54) | CYP2D6CYP1A2CYP3A4NFKB1PNMT | |
| SCHEMBL30678522 | 0.72 | CYP2D6 (0.54) | CYP2D6CYP1A2CYP3A4NFKB1PNMT | |
| SCHEMBL17448132 | 0.72 | CYP2D6 (0.54) | CYP2D6CYP1A2CYP3A4NFKB1PNMT | |
| SCHEMBL30678523 | 0.72 | CYP2D6 (0.54) | CYP2D6CYP1A2CYP3A4NFKB1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040197484-A1 | Coating liquid for forming insulating film and method for producing insulating film | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-10-07 | — | — | US | disclosed |
| US-5385961-A | Coating aminofunctional polysiloxane over solid phosphite core; nonhydrolyzing | GENERAL ELECTRIC COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| EP-0609034-A1 | Amino silicone/phosphite compositions | GENERAL ELECTRIC COMPANY (US) | 1994-08-03 | — | — | EP | disclosed |
| US-4496705-A | TREATING POLYSILOXANE WITH ORGANO-SULTONE | GENERAL ELECTRIC COMPANY (US) | 1985-01-29 | — | — | US | disclosed |