SCHEMBL6695985

SCHEMBL6695985

CCCC(C)n1nnc2cc(C(=O)O)ccc21

nearest known ligand 0.81

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 19/20 0.81
HPGD P15428 1/20 0.71
HCAR2 Q8TDS4 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6044065 0.89 HCAR3 (1.00) HCAR3HPGDHCAR2
SCHEMBL6043965 0.85 HCAR3 (0.78) HCAR3HPGDHCAR2
SCHEMBL839123 0.83 HCAR3 (1.00) HCAR3HPGDHCAR2
SCHEMBL6043960 0.83 HCAR3 (1.00) HCAR3HPGDHCAR2
SCHEMBL6044252 0.82 HCAR3 (1.00) HCAR3HPGDHCAR2
SCHEMBL22622090 0.81 HCAR3 (0.78) HCAR3HPGDHCAR2
SCHEMBL6043783 0.81 HCAR3 (0.78) HCAR3HPGDHCAR2
SCHEMBL6688639 0.79 HCAR3 (0.71) HCAR3HPGDHCAR2
SCHEMBL6043684 0.78 HCAR3 (0.77) HCAR3HPGDHCAR2
SCHEMBL6044709 0.75 HCAR3 (0.69) HCAR3HPGDHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004041274-A1 BENZOTRIAZOLES AND METHODS OF PROPHYLAXIS OR TREATMENT OF METABOLIC-RELATED DISORDERS THEREOF ARENA PHARMACEUTICALS, INC. (US) 2004-05-21 WO disclosed