Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659467 | 1.00 | SLC6A4 (0.49) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 | |
| SCHEMBL5405164 | 0.86 | SLC6A2 (0.55) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 | |
| SCHEMBL5078074 | 0.83 | SLC6A4 (0.59) | SLC6A4 | |
| SCHEMBL6725319 | 0.83 | SLC6A2 (0.68) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 | |
| SCHEMBL9772801 | 0.83 | SLC6A2 (0.68) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 | |
| SCHEMBL14169727 | 0.81 | SLC6A2 (0.48) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 | |
| SCHEMBL6006366 | 0.79 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL17835845 | 0.78 | MAPT (0.49) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 | |
| SCHEMBL17835846 | 0.78 | MAPT (0.49) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 | |
| SCHEMBL8202643 | 0.78 | SLC6A4 (0.61) | SLC6A4SLC6A2MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004064774-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-08-05 | — | — | WO | disclosed |