Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694645 | 0.87 | TSHR (0.61) | TSHRALDH1A1HSD17B10CDC25BMAPT | |
| SCHEMBL6692087 | 0.86 | TSHR (0.51) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL6696656 | 0.86 | TSHR (0.51) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL6689490 | 0.86 | TSHR (0.51) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL6691368 | 0.80 | MAPK1 (0.58) | TSHRALDH1A1HSD17B10MAPTMAPK1 | |
| SCHEMBL28026633 | 0.75 | TSHR (0.56) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL8587612 | 0.74 | TSHR (0.65) | TSHRALDH1A1HSD17B10CDC25BMAPT | |
| SCHEMBL7688461 | 0.74 | KMT2A (0.65) | TSHRALDH1A1HSD17B10CDC25BMAPT | |
| SCHEMBL8498851 | 0.74 | TSHR (0.65) | TSHRALDH1A1HSD17B10CDC25BMAPT | |
| SCHEMBL23773427 | 0.73 | TSHR (0.68) | TSHRALDH1A1HSD17B10CLEC4MCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |