SCHEMBL7688461

SCHEMBL7688461

CCOC(=O)c1cccc(OC)c1OC

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.65
POLB P06746 1/20 0.65
TSHR P16473 2/20 0.59
LMNA P02545 3/20 0.59
MAPT P10636 2/20 0.59
KDM4E B2RXH2 2/20 0.55
HSD17B10 Q99714 3/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
HTT P42858 1/20 0.55
RAB9A P51151 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
TP53 P04637 1/20 0.52
MEN1 O00255 3/20 0.51
CDC25B P30305 1/20 0.51
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23773427 0.90 TSHR (0.68) KMT2APOLBTSHRLMNAMAPT
SCHEMBL16672818 0.86 TSHR (0.56) KMT2APOLBTSHRLMNAMAPT
SCHEMBL11678098 0.86 TSHR (0.63) KMT2APOLBTSHRLMNAMAPT
SCHEMBL11698695 0.85 KMT2A (0.53) KMT2APOLBTSHRLMNAMAPT
SCHEMBL6613660 0.85 KMT2A (0.59) KMT2APOLBTSHRLMNAMAPT
SCHEMBL22685328 0.84 TSHR (0.64) KMT2APOLBTSHRLMNAMAPT
SCHEMBL873499 0.84 TSHR (0.71) KMT2APOLBTSHRLMNAMAPT
SCHEMBL29678391 0.84 TSHR (0.71) KMT2APOLBTSHRLMNAMAPT
SCHEMBL4590566 0.84 LMNA (0.52) KMT2APOLBLMNAMAPTKDM4E
SCHEMBL21612146 0.83 TSHR (0.59) KMT2APOLBTSHRLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772246-A Light-cured resin composition, preparation method and application thereof, light-cured resin material and application thereof 中国石油化工股份有限公司 2023-03-10 CN claimed
CN-105541866-A 2-(4-fluorophenyl)-7-H-thiophene[3minute,2minute:4,5]pyrimidine[6,1-b]quinazoline-7-keto heterocyclic compound and synthetic method thereof Shandong yikang pharmaceutical co ltd 2016-05-04 CN claimed
CN-105218322-A A kind of synthetic method of 3,5-dimethoxybenzoic acid ethyl ester DING YUQIN 2016-01-06 CN claimed
CN-100475805-C Method for synthesizing 3-methyl-7-,8-dihydroxyisochromanone-4 UNIV CHINA PHARMA (CN) 2009-04-08 CN claimed
CN-101016289-A Method of synthesizing 3-methyl-7-,8-dihydroxyisochromanone-4 UNIV CHINA PHARMA (CN) 2007-08-15 CN claimed
CN-115772246-A Light-cured resin composition, preparation method and application thereof, light-cured resin material and application thereof 中国石油化工股份有限公司 2023-03-10 CN disclosed
EP-4119539-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF XWPharma Ltd. (KY) 2023-01-18 EP disclosed
WO-2017049470-A1 PRODRUGS OF GAMMA-HYDROXYBUTYRIC ACID, COMPOSITIONS AND USES THEREOF XW LABORATORIES INC. (CN) 2017-03-30 WO disclosed
CN-105541866-A 2-(4-fluorophenyl)-7-H-thiophene[3minute,2minute:4,5]pyrimidine[6,1-b]quinazoline-7-keto heterocyclic compound and synthetic method thereof Shandong yikang pharmaceutical co ltd 2016-05-04 CN disclosed
CN-103254139-B Novel 18f marks 4-amino quinazoline derivative and preparation method thereof and applies with PET tumor imaging BEIJING NORMAL UNIVERSITY (CN) 2016-04-20 CN disclosed
CN-102939287-B Estrogenic agents and uses thereof ARAGON PHARMACEUTICALS, INC. (US) 2016-01-27 CN disclosed
CN-105218322-A A kind of synthetic method of 3,5-dimethoxybenzoic acid ethyl ester DING YUQIN 2016-01-06 CN disclosed
US-6046189-A ANTI-INFLAMMATORY DRUG, PARTICULARLY, A DRUG FOR PREVENTING OR TREATING ARTHRITIS, A DRUG FOR INHIBITING BONE RESORPTION, IMMUNOSUPPRESSANT TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-04-04 US disclosed
CN-1216546-A Thienopyridine derivatives and their use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-05-12 CN disclosed
EP-0900223-A1 THIENOPYRIDINE DERIVATIVES AND THEIR USE Takeda Chemical Industries, Ltd. (JP) 1999-03-10 EP disclosed
CN-1184105-A Substituted thiazolidine derivatives and pharmaceutical compositions containing them and use thereof OTSUKA PHARMA CO LTD (JP) 1998-06-10 CN disclosed
CN-1037842-C Substituted thiazolidine derivatives, pharmaceutical compositions and uses thereof OTSUKA PHARMA CO LTD (JP) 1998-03-25 CN disclosed
WO-1997040050-A1 THIENOPYRIDINE DERIVATIVES AND THEIR USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-30 WO disclosed
CN-1162958-A Thienopyridine or thienopyrimidine derivatives and their use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1997-10-22 CN disclosed
CN-1106982-A Maillard reaction inhibitor OTSUKA PHARMA CO LTD (JP) 1995-08-16 CN disclosed