Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.50 |
| ▸ | HTR2B | P41595 | 8/20 | 0.50 |
| ▸ | DPP4 | P27487 | 5/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15824978 | 0.84 | TAAR1 (0.43) | HTR2CHTR2BTAAR1HTR2A | |
| SCHEMBL17372630 | 0.82 | HTR2C (0.58) | HTR2CHTR2BDPP4DPP7TAAR1 | |
| SCHEMBL14698726 | 0.81 | HTR2C (0.54) | HTR2CHTR2BTAAR1HTR2AGAA | |
| SCHEMBL30593287 | 0.81 | HTR2C (0.54) | HTR2CHTR2BTAAR1HTR2AGAA | |
| SCHEMBL20556014 | 0.81 | HTR2C (0.39) | HTR2CHTR2BDPP4DPP7HTR2A | |
| SCHEMBL2386164 | 0.81 | DPP4 (0.47) | HTR2CHTR2BDPP4DPP7TAAR1 | |
| Dimethylamine SCHEMBL27980772 | 0.80 | HTR2C (0.47) | HTR2CHTR2BDPP4TAAR1HTR2A | |
| SCHEMBL6015072 | 0.80 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL28773228 | 0.79 | DPP4 (0.46) | HTR2CHTR2BDPP4DPP7TAAR1 | |
| SCHEMBL30502301 | 0.79 | HTR2C (0.44) | HTR2CHTR2BDPP4DPP7TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012024179-A1 | SUBSTITUTED AMIDE DERIVATIVES AS DGAT-1 INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2012-02-23 | — | — | WO | disclosed |