Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.32 |
| ▸ | ITGAV | P06756 | 4/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.32 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6701540 | 0.96 | ITGB3 (0.32) | SMN1; SMN2ALDH1A1KDM4EHPGDCASP1 | |
| SCHEMBL6698124 | 0.88 | ITGB3 (0.46) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6701394 | 0.86 | ITGB3 (0.39) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6695495 | 0.85 | ITGB3 (0.38) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6160985 | 0.84 | MGAM (0.42) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| Trifluoroacetic Acid SCHEMBL6699200 | 0.84 | ITGB3 (0.45) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| Trifluoroacetic Acid SCHEMBL6697687 | 0.82 | ITGAV (0.37) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6162318 | 0.82 | MGAM (0.37) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6698733 | 0.82 | MGAM (0.48) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| Trifluoroacetic Acid SCHEMBL6697083 | 0.81 | ITGB3 (0.37) | ITGB3ITGAVITGB1ITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138284-A1 | Indol-3-yl derivatives | WIESNER MATTHIAS | 2004-07-15 | — | — | US | disclosed |
| US-6743810-B2 | INTEGRIN INHIBITORS; TUMORS, OSTEOPOROSIS, OSTEOLYTIC DISEASES, SUPPRESSING ANGIOGENESIS, ANTITHROMBOTIC | MERCK PATENT GMBH (DE) | 2004-06-01 | — | — | US | disclosed |
| US-20030045728-A1 | Liberating 3-substituted indole compound from one of its functional derivatives by treatment with a solvolyzing or hydrogenating agent, amidation, saponification, alkylation or acylation, or salt formation | MERCK PATENT GMBH (DE) | 2003-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030045728-A1 | Liberating 3-substituted indole compound from one of its functional derivatives by treatment with a solvolyzing or hydrogenating agent, amidation, saponification, alkylation or acylation, or salt formation | IGF1R, IDO1, ITGB3 | SMN1; SMN2 1683/4885ALDH1A1 2063/4885KDM4E 3529/4885 |
| US-20040138284-A1 | Indol-3-yl derivatives | ITGB3, ITGB1, IGF1R | SMN1; SMN2 2180/4885ALDH1A1 2529/4885KDM4E 2672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.