Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 6/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TXN | P10599 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6699266 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TP53NPC1TSHRRAB9A | |
| SCHEMBL6696712 | 0.84 | MEN1 (0.46) | ALDH1A1TP53NPC1TSHRRAB9A | |
| SCHEMBL6694300 | 0.82 | CYP1A2 (0.40) | ALDH1A1NPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL6688611 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TP53SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL6691552 | 0.79 | ALDH1A1 (0.40) | ALDH1A1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL6694941 | 0.78 | ALDH1A1 (0.39) | ALDH1A1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL29351180 | 0.78 | CYP1A2 (0.65) | ALDH1A1NPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL212831 | 0.78 | CYP1A2 (0.65) | ALDH1A1NPC1TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL547028 | 0.76 | ALDH1A1 (0.64) | ALDH1A1TP53NPC1TSHRRAB9A | |
| SCHEMBL11536996 | 0.76 | CYP1A2 (0.63) | ALDH1A1NPC1TSHRRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |