Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312314 | 0.88 | CYP3A4 (0.46) | CYP19A1IDO1ADRA2CALOX15ALDH1A1 | |
| SCHEMBL9367826 | 0.86 | CYP19A1 (0.57) | CYP19A1IDO1ADRA2CALOX15ALDH1A1 | |
| SCHEMBL31180917 | 0.82 | ADRA2C (0.71) | CYP19A1IDO1ADRA2CALOX15CYP3A4 | |
| SCHEMBL6313011 | 0.82 | ADRA2C (0.59) | CYP19A1IDO1ADRA2CALOX15CYP3A4 | |
| SCHEMBL6305279 | 0.82 | ADRA2C (0.71) | CYP19A1IDO1ADRA2CALOX15CYP3A4 | |
| SCHEMBL6305674 | 0.82 | ADRA2C (0.71) | CYP19A1IDO1ADRA2CALOX15CYP3A4 | |
| SCHEMBL29669977 | 0.82 | ADRA2C (0.70) | CYP19A1IDO1ADRA2CAGER | |
| SCHEMBL11277181 | 0.82 | ADRA2C (0.70) | CYP19A1IDO1ADRA2CAGER | |
| SCHEMBL6394302 | 0.80 | ADRA2C (0.44) | CYP19A1IDO1ADRA2CALOX15CYP3A4 | |
| SCHEMBL3670452 | 0.78 | CYP19A1 (0.58) | CYP19A1CYP3A4CYP1A2CYP2D6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040039033-A1 | (1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase | BRISTOL-MYERS SQUIBB COMPANY | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040039033-A1 | (1-phenyl-2-heteroaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase | ATP5F1A, ATP5ME, ATP5F1D | CYP19A1 3335/4885IDO1 3414/4885ADRA2C 783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.