Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5223467 | 0.98 | KDM4E (0.67) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| SCHEMBL1514427 | 0.93 | KDM4E (0.64) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| SCHEMBL5615322 | 0.93 | KDM4E (0.64) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| Hydrochloric Acid SCHEMBL1514615 | 0.91 | KDM4E (0.62) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| SCHEMBL3291180 | 0.89 | KDM4E (0.67) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| SCHEMBL19011668 | 0.85 | KDM4E (0.66) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| SCHEMBL565864 | 0.82 | KDM4E (0.61) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| SCHEMBL3287137 | 0.82 | KDM4E (0.61) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| SCHEMBL30607573 | 0.81 | KDM4E (0.61) | KDM4ERECQLALDH1A1MAPTDRD2 | |
| SCHEMBL3287870 | 0.81 | KDM4E (0.61) | KDM4ERECQLALDH1A1MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | KDM4E 2945/4885RECQL 4374/4885ALDH1A1 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.