Acetic Acid

Acetic Acid

SCHEMBL6697872

C=Cc1ccccc1/C=C/C(=O)O.CC(=O)O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
NFKB1 P19838 1/20 0.56
CA4 P22748 1/20 0.56
MAPT P10636 2/20 0.49
HTT P42858 1/20 0.49
HDAC3 O15379 1/20 0.48
TNKS O95271 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
TNKS2 Q9H2K2 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9817843 0.94 NFKB1 (0.62) CA1CA2NFKB1CA4MAPT
SCHEMBL175543 0.94 NFKB1 (0.62) CA1CA2NFKB1CA4MAPT
Fumaric Acid SCHEMBL11627288 0.84 CA1 (0.52) CA1CA2NFKB1CA4MAPT
Maleic Acid SCHEMBL11627287 0.84 CA1 (0.52) CA1CA2NFKB1CA4MAPT
SCHEMBL69543 0.84 NFKB1 (0.75) CA1CA2NFKB1CA4MAPT
SCHEMBL459291 0.84 NFKB1 (0.75) CA1CA2NFKB1CA4MAPT
SCHEMBL31197561 0.84 NFKB1 (0.75) CA1CA2NFKB1CA4MAPT
Cinnamic Acid SCHEMBL11333815 0.83 HCAR2 (0.73) CA1CA2NFKB1CA4MAPT
Hydrochloric Acid SCHEMBL8374050 0.82 NFKB1 (0.72) CA1CA2NFKB1CA4MAPT
Bromide SCHEMBL8376004 0.82 NFKB1 (0.72) CA1CA2NFKB1CA4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9217920-B2 Photocurable compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-22 US disclosed
US-20150248055-A1 PHOTOCURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-09-03 US disclosed
EP-2892938-A1 PHOTOCURABLE COMPOSITIONS 3M Innovative Properties Company (US) 2015-07-15 EP disclosed
EP-2883109-A1 PHOTOCURABLE COMPOSITIONS 3M Innovative Properties Company (US) 2015-06-17 EP disclosed
EP-2812758-A1 PHOTOCURABLE COMPOSITION 3M Innovative Properties Company (US) 2014-12-17 EP disclosed
US-8883402-B2 Photocurable compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-11-11 US disclosed
US-8715904-B2 Photocurable composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-06 US disclosed
US-8703385-B2 Photoresist composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-22 US disclosed
US-20140048741-A1 FILTRATION MEDIA 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-02-20 US disclosed
WO-2014025716-A1 PHOTOCURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-02-13 WO disclosed
EP-0915736-B1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INC (US) 2003-10-15 EP disclosed
US-6576139-B1 Comprising self-supporting cellulose fibers immobilized with particulate cation exchange resin 3M INNOVATIVE PROPERTIES COMPANY 2003-06-10 US disclosed
US-20030047507-A1 Filter sheet and process for purifying photoresist composition employing the filter sheet 3M INNOVATIVE PROPERTIES COMPANY 2003-03-13 US disclosed
WO-2002000325-A2 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INCORPORATED (US) 2002-01-03 WO disclosed
US-6103122-A FILTRATION OF PHOTORESISTS AND SELF-SUPPORTING FIBER MATRICES CUNO INCORPORATED (US) 2000-08-15 US disclosed
EP-0915736-A1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET Cuno Incorporated (US) 1999-05-19 EP disclosed
WO-1998004348-A1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INCORPORATED (US) 1998-02-05 WO disclosed
US-5525315-A Process for removing heavy metal ions with a chelating cation exchange resin SHIPLEY COMPANY, L.L.C. (US) 1996-06-11 US disclosed
US-5518628-A Purification process SHIPLEY COMPANY INC. (US) 1996-05-21 US disclosed
US-5350714-A Point-of-use purification SHIPLEY COMPANY INC. (US) 1994-09-27 US disclosed