Acetic Acid

Acetic Acid

SCHEMBL6697876

C=CC(=Cc1ccccc1)C(=O)O.CC(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.57
HTT P42858 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47
AKR1C1 Q04828 1/20 0.46
RECQL P46063 1/20 0.44
FBP1 P09467 1/20 0.43
GLA P06280 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
AKT1 P31749 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
MTNR1A P48039 2/20 0.40
MTNR1B P49286 2/20 0.40
TP53 P04637 1/20 0.40
NPC1 O15118 1/20 0.40
POLB P06746 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5332797 0.94 AKR1C3 (0.52) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL175544 0.94 AKR1C3 (0.52) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL15686735 0.86 AKR1C3 (0.53) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL10643208 0.82 AKR1C3 (0.47) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL3258198 0.81 AKT1 (0.50) AKR1C3HTTALDH1A1AKR1C1RECQL
SCHEMBL3803614 0.81 AKR1C3 (0.47) AKR1C3HTTALDH1A1TSHRAKR1C1
SCHEMBL380360 0.79 TP53 (0.40) AKR1C3ALDH1A1AKR1C1TDP1CYP3A4
SCHEMBL10879651 0.78 MEN1 (0.46) AKR1C3ALDH1A1TSHRRECQLMEN1
SCHEMBL28216003 0.78 MEN1 (0.46) AKR1C3ALDH1A1TSHRRECQLMEN1
SCHEMBL10360240 0.78 MEN1 (0.46) AKR1C3ALDH1A1TSHRRECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9217920-B2 Photocurable compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-12-22 US disclosed
US-20150248055-A1 PHOTOCURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-09-03 US disclosed
EP-2892938-A1 PHOTOCURABLE COMPOSITIONS 3M Innovative Properties Company (US) 2015-07-15 EP disclosed
EP-2883109-A1 PHOTOCURABLE COMPOSITIONS 3M Innovative Properties Company (US) 2015-06-17 EP disclosed
EP-2812758-A1 PHOTOCURABLE COMPOSITION 3M Innovative Properties Company (US) 2014-12-17 EP disclosed
US-8883402-B2 Photocurable compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-11-11 US disclosed
US-8715904-B2 Photocurable composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-05-06 US disclosed
US-8703385-B2 Photoresist composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-22 US disclosed
US-20140048741-A1 FILTRATION MEDIA 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-02-20 US disclosed
US-20140044932-A1 PHOTOCURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2014-02-13 US disclosed
EP-0915736-B1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INC (US) 2003-10-15 EP disclosed
US-6576139-B1 Comprising self-supporting cellulose fibers immobilized with particulate cation exchange resin 3M INNOVATIVE PROPERTIES COMPANY 2003-06-10 US disclosed
US-20030047507-A1 Filter sheet and process for purifying photoresist composition employing the filter sheet 3M INNOVATIVE PROPERTIES COMPANY 2003-03-13 US disclosed
WO-2002000325-A2 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INCORPORATED (US) 2002-01-03 WO disclosed
US-6103122-A FILTRATION OF PHOTORESISTS AND SELF-SUPPORTING FIBER MATRICES CUNO INCORPORATED (US) 2000-08-15 US disclosed
EP-0915736-A1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET Cuno Incorporated (US) 1999-05-19 EP disclosed
WO-1998004348-A1 FILTER SHEET AND PROCESS FOR PURIFYING PHOTORESIST COMPOSITION EMPLOYING THE FILTER SHEET CUNO INCORPORATED (US) 1998-02-05 WO disclosed
US-5525315-A Process for removing heavy metal ions with a chelating cation exchange resin SHIPLEY COMPANY, L.L.C. (US) 1996-06-11 US disclosed
US-5518628-A Purification process SHIPLEY COMPANY INC. (US) 1996-05-21 US disclosed
US-5350714-A Point-of-use purification SHIPLEY COMPANY INC. (US) 1994-09-27 US disclosed