Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694327 | 0.90 | RAB9A (0.34) | KMT2AMEN1NPC1ALDH1A1HSD17B10 | |
| SCHEMBL6693731 | 0.89 | KMT2A (0.37) | KMT2AMEN1APOBEC3GNPC1NQO1 | |
| SCHEMBL6690962 | 0.88 | MEN1 (0.41) | KMT2AMEN1APOBEC3GNPC1ALDH1A1 | |
| SCHEMBL6691267 | 0.86 | NQO1 (0.34) | KMT2AMEN1APOBEC3GNPC1NQO1 | |
| SCHEMBL6691232 | 0.82 | MEN1 (0.35) | KMT2AMEN1APOBEC3GNPC1NQO1 | |
| SCHEMBL6690282 | 0.78 | SMN1; SMN2 (0.38) | KMT2AMEN1APOBEC3GNPC1ALDH1A1 | |
| SCHEMBL6691825 | 0.77 | SNCA (0.40) | KMT2AMEN1APOBEC3GNPC1ALDH1A1 | |
| SCHEMBL6698691 | 0.76 | HTR2A (0.33) | KMT2AMEN1NPC1ALDH1A1TSHR | |
| SCHEMBL6690892 | 0.76 | NQO1 (0.34) | KMT2AMEN1APOBEC3GNPC1NQO1 | |
| SCHEMBL6694898 | 0.74 | MAPT (0.39) | KMT2AMEN1APOBEC3GALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |