Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4959475 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10MAPK1ALOX15 | |
| SCHEMBL30702637 | 0.82 | ALDH1A1 (0.70) | ALDH1A1HPGDHSD17B10MAPTPOLB | |
| SCHEMBL2307143 | 0.82 | ALDH1A1 (0.70) | ALDH1A1HPGDHSD17B10MAPTPOLB | |
| SCHEMBL19004112 | 0.82 | ALDH1A1 (0.53) | ALDH1A1HPGDHSD17B10MAPK1ALOX15 | |
| SCHEMBL10517748 | 0.81 | HPGD (1.00) | ALDH1A1HPGDHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL96123 | 0.81 | HPGD (1.00) | ALDH1A1HPGDHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL11424223 | 0.80 | ALDH1A1 (0.68) | ALDH1A1HPGDHSD17B10MAPK1POLB | |
| SCHEMBL14817806 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HPGDHSD17B10MAPK1MAPT | |
| SCHEMBL23705971 | 0.78 | RXFP1 (0.51) | ALDH1A1HPGDHSD17B10MAPK1ALOX15 | |
| SCHEMBL909725 | 0.78 | HSD17B10 (0.56) | ALDH1A1HPGDHSD17B10MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950669-B1 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM & HAAS (US) | 2004-09-08 | — | — | EP | disclosed |
| US-6306991-B1 | TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS | ROHM AND HAAS COMPANY | 2001-10-23 | — | — | US | disclosed |
| US-6149977-A | CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. | ROHM AND HAAS COMPANY (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0950669-A2 | Method of catalytic crosslinking of polymers and two-pack composition used therein | ROHM AND HAAS COMPANY (US) | 1999-10-20 | — | — | EP | disclosed |