Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6698258 | 1.00 | PTPRZ1 (0.54) | PTPRZ1MAOBSCN9AMAOAPPARG | |
| SCHEMBL6691341 | 0.93 | PTPRZ1 (0.53) | PTPRZ1MAOBSCN9AMAOAPPARG | |
| SCHEMBL6687904 | 0.86 | MAOB (0.56) | MAOB | |
| SCHEMBL6687900 | 0.86 | MAOB (0.56) | MAOB | |
| SCHEMBL6694003 | 0.84 | BCHE (0.44) | PTPRZ1 | |
| SCHEMBL6694007 | 0.84 | BCHE (0.44) | PTPRZ1 | |
| SCHEMBL6685877 | 0.83 | MAOB (0.61) | PTPRZ1MAOBSCN9AMAOA | |
| SCHEMBL6685873 | 0.83 | MAOB (0.61) | PTPRZ1MAOBSCN9AMAOA | |
| SCHEMBL6694094 | 0.82 | PTPRZ1 (0.52) | PTPRZ1MAOBSCN9AMAOA | |
| SCHEMBL6689649 | 0.80 | MAOB (0.51) | PTPRZ1MAOBMAOAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |