Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687535 | 0.88 | ITGA4 (0.44) | MAOBMAOAPTPRZ1PPARG | |
| SCHEMBL6691341 | 0.87 | PTPRZ1 (0.53) | MAOBMAOAPTPRZ1PPARGGPR34 | |
| SCHEMBL6696899 | 0.87 | MAOB (0.52) | MAOBMAOAPTPRZ1PTPN1 | |
| SCHEMBL6687567 | 0.81 | PPARG (0.42) | PTPRZ1PPARG | |
| SCHEMBL6687562 | 0.81 | PPARG (0.42) | PTPRZ1PPARG | |
| SCHEMBL6698258 | 0.80 | PTPRZ1 (0.54) | MAOBMAOAPTPRZ1PPARG | |
| SCHEMBL6698255 | 0.80 | PTPRZ1 (0.54) | MAOBMAOAPTPRZ1PPARG | |
| SCHEMBL6685527 | 0.79 | FFAR4 (0.48) | PPARG | |
| SCHEMBL6685530 | 0.79 | FFAR4 (0.48) | PPARG | |
| SCHEMBL6687186 | 0.76 | MAOB (0.46) | MAOBMAOAPTPRZ1S1PR1PRKX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |