Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18232436 | 1.00 | HRH4 (0.42) | HRH4HRH3EPHX1PKMANPEP | |
| SCHEMBL6693280 | 0.98 | HRH4 (0.41) | HRH4HRH3EPHX1PKMANPEP | |
| SCHEMBL6692244 | 0.90 | — | — | |
| SCHEMBL24379824 | 0.87 | HRH4 (0.48) | HRH4HRH3EPHX1PKMANPEP | |
| SCHEMBL5298781 | 0.87 | HRH4 (0.48) | HRH4HRH3EPHX1PKMANPEP | |
| SCHEMBL2483497 | 0.87 | HRH4 (0.48) | HRH4HRH3EPHX1PKMANPEP | |
| SCHEMBL9624660 | 0.84 | HRH4 (0.47) | HRH4HRH3EPHX1PKMANPEP | |
| SCHEMBL9494047 | 0.84 | KMT2A (0.41) | PKMANPEPERAP2LMNAALDH1A1 | |
| SCHEMBL20996688 | 0.81 | KMT2A (0.41) | PKMANPEPERAP2LMNAALDH1A1 | |
| SCHEMBL605994 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004533516-A | — | — | 2004-11-04 | — | — | JP | claimed |
| US-20040134838-A1 | Method of refining crude oils having organic acidity | TOTAL FRANCE (FR) | 2004-07-15 | — | — | US | claimed |
| EP-1397468-A1 | METHOD OF REFINING CRUDE OILS HAVING HIGH ORGANIC ACIDITY | Total France (FR) | 2004-03-17 | — | — | EP | claimed |
| WO-2002097014-A1 | METHOD OF REFINING CRUDE OILS HAVING HIGH ORGANIC ACIDITY | TOTAL FRANCE (FR) | 2002-12-05 | — | — | WO | claimed |
| US-10899754-B2 | Modulators of indoleamine 2,3-dioxygenase | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-01-26 | — | — | US | disclosed |
| US-20200115374-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-04-16 | — | — | US | disclosed |
| EP-3558978-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-10-30 | — | — | EP | disclosed |
| WO-2018116107-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-06-28 | — | — | WO | disclosed |
| US-20040134838-A1 | Method of refining crude oils having organic acidity | TOTAL FRANCE (FR) | 2004-07-15 | — | — | US | disclosed |
| EP-1397468-A1 | METHOD OF REFINING CRUDE OILS HAVING HIGH ORGANIC ACIDITY | Total France (FR) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002097014-A1 | METHOD OF REFINING CRUDE OILS HAVING HIGH ORGANIC ACIDITY | TOTAL FRANCE (FR) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200115374-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | HRH4 2848/4885HRH3 2321/4885EPHX1 1936/4885 |
| US-10899754-B2 | Modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, INMT | HRH4 2848/4885HRH3 2321/4885EPHX1 1936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.