Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.44 |
| ▸ | ABL1 | P00519 | 13/20 | 0.44 |
| ▸ | EGFR | P00533 | 13/20 | 0.44 |
| ▸ | HCK | P08631 | 13/20 | 0.44 |
| ▸ | SRC | P12931 | 13/20 | 0.44 |
| ▸ | KDR | P35968 | 13/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.44 |
| ▸ | MTOR | P42345 | 13/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 13/20 | 0.44 |
| ▸ | PRKDC | P78527 | 13/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 12/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4030477 | 0.85 | ESR1 (0.70) | ESR1PIK3CDABL1EGFRHCK | |
| SCHEMBL4029561 | 0.83 | ESR1 (0.44) | ESR1APPALOX5IDO1 | |
| SCHEMBL4027041 | 0.80 | ESR1 (0.60) | ESR1PIK3CDABL1EGFRHCK | |
| SCHEMBL4026032 | 0.80 | ESR1 (0.60) | ESR1PIK3CDABL1EGFRHCK | |
| SCHEMBL5397335 | 0.78 | ESR1 (0.51) | ESR1PIK3CDABL1EGFRHCK | |
| SCHEMBL5397380 | 0.78 | ESR1 (0.56) | ESR1KMT2AAPPALOX5 | |
| SCHEMBL4035727 | 0.76 | ESR1 (0.57) | ESR1KMT2A | |
| SCHEMBL4026000 | 0.75 | ESR1 (0.73) | ESR1PIK3CDABL1EGFRHCK | |
| SCHEMBL4035132 | 0.75 | ESR1 (0.56) | ESR1 | |
| SCHEMBL4028977 | 0.73 | ESR1 (0.64) | ESR1PIK3CDABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167127-A1 | Substituted 4-(indazol-3-yl)phenols | WYETH (US) | 2004-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167127-A1 | Substituted 4-(indazol-3-yl)phenols | INSR, MSR1, TNNI3 | ESR1 2487/4885PIK3CD 2207/4885ABL1 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.