Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | MGAM | O43451 | 3/20 | 0.52 |
| ▸ | SI | P14410 | 3/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27998563 | 0.87 | MAOB (0.59) | MAOBPDGFRBPDGFRAGAAMGAM | |
| SCHEMBL25282560 | 0.86 | MAOB (0.57) | MAOBPDGFRBPDGFRAGAAMEN1 | |
| SCHEMBL6696628 | 0.86 | MAOB (0.57) | MAOBPDGFRBPDGFRAGAAMEN1 | |
| SCHEMBL2094271 | 0.84 | MAOB (0.59) | MAOBPDGFRBPDGFRAGAAMGAM | |
| SCHEMBL4599002 | 0.83 | MAOB (0.54) | MAOBPDGFRBPDGFRAGAAMEN1 | |
| SCHEMBL23906959 | 0.82 | MAOB (0.79) | MAOBGAAMEN1KMT2AALOX5 | |
| SCHEMBL18623122 | 0.82 | MAOB (0.62) | MAOBPDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL2090976 | 0.82 | MAOB (0.62) | MAOBPDGFRBPDGFRAKMT2AALOX5 | |
| SCHEMBL1745424 | 0.82 | MAOB (0.53) | MAOBPDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL10665635 | 0.82 | MAOB (0.53) | MAOBPDGFRBPDGFRAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147597-A1 | Anti-mycobacterium compositions and methods of preparing and using same | ADVANCED LIFE SCIENCES, INC. | 2004-07-29 | — | — | US | disclosed |
| US-6677350-B1 | ADMINISTERING CHALCONE-LIKE VINYLCARBONYL COMPOUNDS TO PREVENT OR TREAT MYCOBACTERIUM INFECTIONS/TUBERCULOSIS | ADVANCED LIFE SCIENCES, INC. | 2004-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147597-A1 | Anti-mycobacterium compositions and methods of preparing and using same | IMMT, CYP51A1, LSS | MAOB 1715/4885PDGFRB 4749/4885PDGFRA 4816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.