Ethylene Glycol

Ethylene Glycol

SCHEMBL6701397

CCOC(=O)c1ccc(Oc2ccc(C(=O)OCC)cc2)cc1.OCCO

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA7 P43166 2/20 0.61
CA9 Q16790 2/20 0.61
CA14 Q9ULX7 2/20 0.61
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
LMNA P02545 2/20 0.59
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
MAOA P21397 1/20 0.59
STS P08842 1/20 0.58
HPGD P15428 4/20 0.53
HTT P42858 2/20 0.53
TSHR P16473 3/20 0.52
POLB P06746 2/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8656770 0.94 CA12 (0.68) CA12CA1CA2CA7CA9
Ethylene Glycol SCHEMBL1538248 0.90 CA1 (0.73) CA12CA1CA2CA7CA9
SCHEMBL9923544 0.89 CA12 (0.61) CA12CA1CA2CA7CA9
SCHEMBL8018978 0.88 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL8059469 0.87 CA1 (0.59) CA12CA1CA2CA7CA9
SCHEMBL9664813 0.87 MAPT (0.68) CA12CA1CA2CA7CA9
SCHEMBL5837526 0.87 MAPT (0.59) CA12CA1CA2CA7CA9
SCHEMBL21656957 0.87 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL5506811 0.87 ESR1 (0.82) CA12CA1CA2CA7CA9
SCHEMBL1730420 0.87 SMN1; SMN2 (0.66) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040106005-A1 Luminescent element SANYO ELECTRIC CO., LTD. (JP) 2004-06-03 US claimed
CN-105532716-A Delonix regia insecticide ZHANG YUANYUAN 2016-05-04 CN disclosed
US-20040106005-A1 Luminescent element SANYO ELECTRIC CO., LTD. (JP) 2004-06-03 US disclosed