Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | STS | P08842 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656770 | 0.93 | CA12 (0.68) | MAPTHPGDRAB9ACA12CA1 | |
| SCHEMBL54211 | 0.91 | CA1 (0.70) | MAPTHPGDRAB9ACA12CA1 | |
| SCHEMBL9923544 | 0.87 | CA12 (0.61) | MAPTHPGDRAB9ACA12CA1 | |
| Ethylene Glycol SCHEMBL6701397 | 0.87 | CA12 (0.61) | MAPTHPGDRAB9ACA12CA1 | |
| SCHEMBL5465044 | 0.86 | MAPT (0.61) | MAPTHPGDRAB9ACA12CA1 | |
| SCHEMBL5506811 | 0.86 | ESR1 (0.82) | MAPTRAB9ACA12CA1CA2 | |
| SCHEMBL21656957 | 0.86 | CA12 (0.59) | MAPTHPGDRAB9ACA12CA1 | |
| SCHEMBL8059469 | 0.86 | CA1 (0.59) | MAPTHPGDRAB9ACA12CA1 | |
| SCHEMBL5837526 | 0.86 | MAPT (0.59) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL1730420 | 0.86 | SMN1; SMN2 (0.66) | MAPTHPGDRAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324472-B1 | KETENEDITHIOACETAL DERIVATIVES AND PROCESSES FOR PRODUCING THE SAME AS WELL AS A COMPOSITION CONTAINING THE SAME | NIHON NOHYAKU CO., LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-5098928-A | Antilipemic agents and treatment of arteriosclerosis | NIHON NOHYAKU CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0324472-A2 | Ketenedithioacetal derivatives and processes for producing the same as well as a composition containing the same | NIHON NOHYAKU CO., LTD. (JP) | 1989-07-19 | — | — | EP | disclosed |