Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL4164753 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL30208060 | 1.00 | TSHR (0.36) | TSHRALDH1A1LMNABLMKMT2A | |
| Benzene SCHEMBL28307809 | 0.89 | GLRA1 (0.33) | TSHRLMNABLMKMT2AGLRA1 | |
| Formic Acid SCHEMBL31377043 | 0.86 | — | — | |
| Monoethanolamine SCHEMBL193700 | 0.84 | — | — | |
| Formic Acid SCHEMBL23405876 | 0.83 | CTH (0.32) | TSHRLMNA | |
| Acetic Acid SCHEMBL27845655 | 0.83 | FFAR3 (0.44) | TSHRALDH1A1LMNABLMKMT2A | |
| Formic Acid SCHEMBL7715351 | 0.82 | — | — | |
| Monoethanolamine SCHEMBL4305455 | 0.81 | — | — | |
| Propylamine SCHEMBL976449 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650634-B | Plant-mixed cold-recycling mixture and road surface layer construction method | 山东建筑大学 | 2023-11-21 | — | — | CN | claimed |
| CN-115650634-A | Plant-mixed cold-recycling mixture and road surface construction method | 山东建筑大学 | 2023-01-31 | — | — | CN | claimed |
| CN-114057989-A | Foamable composite material composition, foamed composite material, and preparation method and application thereof | 国家能源投资集团有限责任公司 | 2022-02-18 | — | — | CN | claimed |
| CN-109535368-B | Low-temperature-resistant polyurethane microporous material and preparation method thereof | 东北师范大学 | 2020-12-11 | — | — | CN | claimed |
| CN-108752552-B | Preparation method of branched waterborne polyurethane nanocomposite | 上海华谊精细化工有限公司 | 2020-12-01 | — | — | CN | claimed |
| CN-116396012-B | Warm-mix high-modulus modified asphalt mixture, production process and production device | 中冶路桥建设有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115650634-B | Plant-mixed cold-recycling mixture and road surface layer construction method | 山东建筑大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-116396012-A | Warm-mix high-modulus modified asphalt mixture, production process and production device | 中冶路桥建设有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-115650634-A | Plant-mixed cold-recycling mixture and road surface construction method | 山东建筑大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-114057989-A | Foamable composite material composition, foamed composite material, and preparation method and application thereof | 国家能源投资集团有限责任公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-109535368-B | Low-temperature-resistant polyurethane microporous material and preparation method thereof | 东北师范大学 | 2020-12-11 | — | — | CN | disclosed |
| CN-108752552-B | Preparation method of branched waterborne polyurethane nanocomposite | 上海华谊精细化工有限公司 | 2020-12-01 | — | — | CN | disclosed |
| US-20040126559-A1 | Ink wastage absorber and ink supporter | BRIDGESTONE CORPORATION | 2004-07-01 | — | — | US | disclosed |
| US-6699423-B2 | FLEXIBLE POLYURETHANE FOAM HAVING AN AIR-PERMEABILITY OF 1.0 CC/CM2/SEC OR MORE. | BRIDGESTONE CORPORATION (JP) | 2004-03-02 | — | — | US | disclosed |
| US-20020055549-A1 | Ink wastage absorber and ink supporter | BRIDGESTONE CORPORATION | 2002-05-09 | — | — | US | disclosed |
| US-6384097-B1 | HAVING LESS ODOR, AND PRODUCING FOAMS OF HIGH FIRE RETARDANCE, HAVING HIGH CURABILITY, HIGH RETARDING EFFECT, AND LOW CORROSIVENESS. | TOSOH CORPORATION (JP) | 2002-05-07 | — | — | US | disclosed |
| US-6337354-B1 | Ink wastage absorber and ink supporter | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| US-6307102-B1 | QUATERNARY AMMONIUM SALT OF AN ALKYLENEPOLYAMINE AND CARBONIC OR A CARBOXYLIC ACID | TOSOH CORPORATION (JP) | 2001-10-23 | — | — | US | disclosed |
| US-5416123-A | Polyurethane foam prepared from high concentration-low viscosity polymer-polyol | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-05-16 | — | — | US | disclosed |
| US-4450246-A | TERTIARY AMINE SALT | W. R. GRACE & CO. (US) | 1984-05-22 | — | — | US | disclosed |