Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 5/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.52 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6703186 | 0.99 | GRM8 (0.51) | GRM6GRM2GRM3GRM8SLC1A2 | |
| SCHEMBL6704928 | 0.83 | GRM2 (0.54) | GRM6GRM2GRM3GRM8SLC1A2 | |
| SCHEMBL6704243 | 0.82 | GRM6 (0.52) | GRM6GRM2GRM3GRM8SLC1A2 | |
| SCHEMBL6701165 | 0.80 | GRM8 (0.50) | GRM6GRM2GRM3GRM8SLC1A2 | |
| SCHEMBL6700199 | 0.77 | GRM2 (0.49) | GRM6GRM2GRM3GRM8SLC1A2 | |
| SCHEMBL6697973 | 0.76 | GRM2 (0.67) | GRM6GRM2GRM3GRM8SLC1A2 | |
| Hydrochloric Acid SCHEMBL6704590 | 0.76 | GRM2 (0.48) | GRM6GRM2GRM3GRM8SLC1A2 | |
| SCHEMBL16610524 | 0.75 | GRM2 (0.55) | GRM2GRM3GRM8 | |
| Hydrochloric Acid SCHEMBL6699648 | 0.75 | GRM2 (0.65) | GRM6GRM2GRM3GRM8SLC1A2 | |
| SCHEMBL8354226 | 0.73 | SLC1A2 (0.44) | GRM6GRM2GRM3GRM8SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248963-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248963-A1 | Prodrugs of excitatory amino acids | SLC1A2, SLC1A1, SLC1A3 | GRM6 33/4885GRM2 20/4885GRM3 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.