Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8354012 | 0.90 | SLC1A2 (0.42) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6704928 | 0.89 | GRM2 (0.54) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6703430 | 0.83 | SLC1A2 (0.55) | GRM8GRM6GRM2GRM3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6703425 | 0.82 | SLC1A2 (0.53) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6704243 | 0.80 | GRM6 (0.52) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL6701797 | 0.80 | GRM6 (0.52) | GRM8GRM6GRM2GRM3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6702822 | 0.80 | SLC1A2 (0.38) | GRM8GRM6GRM2GRM3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6703186 | 0.79 | GRM8 (0.51) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL8354226 | 0.79 | SLC1A2 (0.44) | GRM8GRM6GRM2GRM3SLC1A2 | |
| SCHEMBL8358720 | 0.76 | SLC1A2 (0.44) | GRM8GRM6GRM2GRM3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248963-A1 | Prodrugs of excitatory amino acids | ELI LILLY AND COMPANY | 2004-12-09 | — | — | US | disclosed |
| WO-2003045898-A1 | PRODRUGS OF EXCITATORY AMINO ACIDS | ELI LILLY AND COMPANY (US) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248963-A1 | Prodrugs of excitatory amino acids | SLC1A2, SLC1A1, SLC1A3 | GRM8 52/4885GRM6 33/4885GRM2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.