Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521457 | 0.94 | MTNR1A (0.44) | MTNR1AMTNR1BAOC3L3MBTL1CASR | |
| SCHEMBL11618534 | 0.85 | AOC3 (0.46) | MTNR1AMTNR1BAOC3L3MBTL1CASR | |
| SCHEMBL6055156 | 0.83 | AOC3 (0.60) | MTNR1AMTNR1BAOC3L3MBTL1ALOX5 | |
| SCHEMBL14441698 | 0.83 | CASR (0.47) | MTNR1AMTNR1BAOC3L3MBTL1CASR | |
| SCHEMBL3080355 | 0.82 | AOC3 (0.50) | MTNR1AMTNR1BAOC3L3MBTL1CASR | |
| SCHEMBL4480833 | 0.82 | AOC3 (0.44) | MTNR1AMTNR1BAOC3L3MBTL1CASR | |
| SCHEMBL11617561 | 0.82 | AOC3 (0.44) | MTNR1AMTNR1BAOC3L3MBTL1CASR | |
| SCHEMBL18937394 | 0.82 | AOC3 (0.44) | MTNR1AMTNR1BAOC3L3MBTL1CASR | |
| SCHEMBL27276871 | 0.81 | AOC3 (0.43) | MTNR1AMTNR1BAOC3L3MBTL1CASR | |
| SCHEMBL11619991 | 0.80 | AOC3 (0.45) | MTNR1AMTNR1BAOC3L3MBTL1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040010036-A1 | N,N, -Substituted s-Aryl-Isothioureas, N,N,N, -Substituted s-Aryl-Isothioureas and combinatorial libraries thereof | LION BIOSCIENCE AG (DE) | 2004-01-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010036-A1 | N,N, -Substituted s-Aryl-Isothioureas, N,N,N, -Substituted s-Aryl-Isothioureas and combinatorial libraries thereof | NCL, NISCH, NCSTN | MTNR1A 2741/4885MTNR1B 2629/4885AOC3 3167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.