⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126174 | 1.00 | — | — | |
| SCHEMBL18966423 | 1.00 | — | — | |
| SCHEMBL25009038 | 0.89 | TSHR (0.33) | — | |
| Bicarbonate SCHEMBL11211321 | 0.89 | ALDH1A1 (0.39) | — | |
| SCHEMBL14256219 | 0.81 | — | — | |
| SCHEMBL24884263 | 0.79 | — | — | |
| SCHEMBL11960793 | 0.75 | — | — | |
| SCHEMBL18900142 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL21689714 | 0.75 | — | — | |
| SCHEMBL20942867 | 0.75 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053925-A1 | Novel urea derivatives, method for preparing same, use thereof as medicines, pharmaceutical compositions and novel use | PROSKELIA SAS (FR) | 2004-03-18 | — | — | US | disclosed |
| EP-1358171-A2 | NOVEL UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE | Aventis Pharma S.A. (FR) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059102-A2 | UREA DERIVATIVES, METHOD FOR PREPARING SAME, USE THEREOF AS MEDICINES, PHARMACEUTICAL COMPOSITIONS AND USE | AVENTIS PHARMA S.A. (FR) | 2002-08-01 | — | — | WO | disclosed |
| EP-0050445-B1 | TELOMERIZATION OF BUTADIENE AND CARBON DIOXIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-30 | — | — | EP | disclosed |
| US-4393224-A | Telomerization of butadiene and carbon dioxide | IMPERIAL CHEMICAL INDUSTRIES PLC. (GB) | 1983-07-12 | — | — | US | disclosed |
| EP-0050445-A1 | Telomerization of butadiene and carbon dioxide | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-04-28 | — | — | EP | disclosed |