Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.48 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572246 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL29411296 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL1158129 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL1157909 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL3495263 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL7609463 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL9437254 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL3495447 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL8574512 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK | |
| SCHEMBL28201959 | 0.98 | GPR84 (0.53) | GPR84FFAR1MAPTTP53LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119278054-A | Glycosylated prodrugs | 莱顿大学 | 2025-01-07 | — | — | CN | disclosed |
| CN-119012999-A | Improved nasal administration of pharmaceutical formulations | 思瑞诺医疗有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-115844903-A | Application of betulin derivative in preparation of bacteria inhibiting medicine | 潍坊赛宝工业技术研究院有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114206396-A | Methods and compositions for attenuating an immune response against an antiviral transfer vector | 西莱克塔生物科技公司 | 2022-03-18 | — | — | CN | disclosed |
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | GPR84 3246/4885FFAR1 4188/4885MAPT 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.