SCHEMBL6702847

SCHEMBL6702847

CC(C)=CC1CCCC(O)C1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
LMNA P02545 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2294086 0.78
SCHEMBL30097900 0.77 TSHR (0.40) TSHR
SCHEMBL11102174 0.76
SCHEMBL12166906 0.74 TSHR (0.33) TSHRLMNACYP2C9
SCHEMBL20111411 0.74 DPP4 (0.34)
SCHEMBL607401 0.74 TSHR (0.35) TSHR
SCHEMBL9502830 0.73
SCHEMBL19285512 0.73
SCHEMBL19284963 0.73
SCHEMBL22252672 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120323198-A1 ARTICLES COMPRISING A MINT ODOR-FREE COOLING AGENT PESCE ANTONELLA (IT) 2012-12-20 US claimed
US-20040081680-A1 Articles comprising a mint odor-free cooling agent THE PROCTER & GAMBLE COMPANY 2004-04-29 US claimed
WO-2002083192-A1 ARTICLES COMPRISING A MINT ODOR-FREE COOLING AGENT THE PROCTER & GAMBLE COMPANY (US) 2002-10-24 WO claimed
EP-1250941-A1 Articles comprising a mint odor-free cooling agent THE PROCTER & GAMBLE COMPANY (US) 2002-10-23 EP claimed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 US disclosed
US-9072676-B2 Cyclohexyl carbamate compounds as skin and/or hair lightening actives SYMRISE AG (DE) 2015-07-07 US disclosed
US-9012497-B2 Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE AG (DE) 2015-04-21 US disclosed
US-9012497-B2 Cyclohexyl carbamate compounds as active anti-cellulite ingredients SYMRISE AG (DE) 2015-04-21 US disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 US disclosed
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES SYMRISE AG (DE) 2013-06-20 US disclosed
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2013-05-30 US disclosed
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS SYMRISE AG (DE) 2013-05-30 US disclosed
EP-2389922-A1 Cyclohexyl carbamate compounds as anti-ageing actives Symrise AG (DE) 2011-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130156710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES CBR1, CYP2A13, CBR3 TSHR 579/4885LMNA 1211/4885CYP2C9 36/4885
US-20040081680-A1 Articles comprising a mint odor-free cooling agent NAPRT, TAAR1, PNN TSHR 1580/4885LMNA 3685/4885CYP2C9 2265/4885
US-20130137710-A1 CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS CBR1, NCOR2, CECR2 TSHR 1124/4885LMNA 2360/4885CYP2C9 203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.