Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PLTP | P55058 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703565 | 0.94 | TRPV4 (0.35) | TRPV4MAPTTP53PLTPSCD | |
| SCHEMBL1008694 | 0.91 | TRPV4 (0.36) | TRPV4MAPTTP53PLTPGAA | |
| SCHEMBL29403637 | 0.91 | TRPV4 (0.36) | TRPV4MAPTTP53PLTPGAA | |
| Diethylamine SCHEMBL7031731 | 0.88 | TRPV4 (0.34) | TRPV4MAPTTP53PLTPGAA | |
| Trifluoroacetic Acid SCHEMBL30480661 | 0.88 | TRPV4 (0.34) | TRPV4MAPTTP53PLTPPI4KB | |
| Trifluoroacetic Acid SCHEMBL226079 | 0.88 | TRPV4 (0.34) | TRPV4MAPTTP53PLTPPI4KB | |
| Monoethanolamine SCHEMBL7032257 | 0.88 | TRPV4 (0.34) | TRPV4MAPTTP53PLTPPI4KB | |
| SCHEMBL6700555 | 0.87 | TRPV4 (0.35) | TRPV4MAPTPLTPPI4KBRORC | |
| Diethanolamine SCHEMBL7021233 | 0.87 | TRPV4 (0.33) | TRPV4PLTPPI4KB | |
| Monoethanolamine SCHEMBL7031750 | 0.87 | TRPV4 (0.33) | TRPV4PLTPPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040198793-A1 | Chemical process and new intermediates | SANOFI-SYNTHELABO (FR) | 2004-10-07 | — | — | US | disclosed |
| CN-1478075-A | Chemical process and new intermediates | ��ŵ�Ѻϳ�ʵ���� | 2004-02-25 | — | — | CN | disclosed |
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |