Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688511 | 0.84 | ALDH1A1 (0.76) | ALDH1A1LMNAHTTCYP2C19CYP2C9 | |
| SCHEMBL6695424 | 0.83 | ALDH1A1 (0.81) | ALDH1A1LMNAHTTCYP2C19CYP2C9 | |
| SCHEMBL6694168 | 0.82 | ALDH1A1 (1.00) | ALDH1A1LMNAHTTCYP2C19CYP2C9 | |
| SCHEMBL6695528 | 0.81 | CYP1A2 (1.00) | ALDH1A1LMNAHTTCYP2C19CYP2C9 | |
| SCHEMBL23052379 | 0.79 | ALDH1A1 (0.65) | ALDH1A1LMNAHTTCYP2C19CYP2C9 | |
| SCHEMBL6670526 | 0.76 | ALDH1A1 (0.70) | ALDH1A1LMNAHTTCYP2C19CYP2C9 | |
| SCHEMBL6673517 | 0.74 | ALDH1A1 (0.86) | ALDH1A1LMNAHTTCYP2C19CYP2C9 | |
| SCHEMBL6680626 | 0.74 | ALDH1A1 (0.83) | ALDH1A1LMNAHTTCYP2C19CYP2C9 | |
| SCHEMBL7233324 | 0.74 | SMN1; SMN2 (0.64) | ALDH1A1HTTCYP2C19CYP2C9MAPT | |
| SCHEMBL6670346 | 0.74 | CA12 (0.74) | ALDH1A1LMNAHTTCYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037248-A2 | MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY | CAREX SA (FR) | 2004-05-06 | — | — | WO | disclosed |