Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 4/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | RAD1 | O60671 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | LTA | P01374 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18245192 | 0.76 | P2RY6 (0.41) | P2RY6MIFRAD1PNMTHSD17B10 | |
| SCHEMBL6895988 | 0.72 | P2RY6 (0.50) | P2RY6MIFRAD1PNMTHSD17B10 | |
| SCHEMBL15574008 | 0.71 | P2RY6 (0.39) | P2RY6MIFRAD1PNMTHSD17B10 | |
| SCHEMBL18245093 | 0.71 | P2RY6 (0.40) | P2RY6MIFRAD1PNMTHSD17B10 | |
| Bitoscanate SCHEMBL157128 | 0.69 | MIF (0.72) | P2RY6MIFRAD1PNMTHSD17B10 | |
| SCHEMBL330976 | 0.69 | P2RY6 (0.38) | P2RY6MIFRAD1PNMTHSD17B10 | |
| SCHEMBL4330324 | 0.68 | P2RY6 (0.37) | P2RY6MIFRAD1PNMTHSD17B10 | |
| SCHEMBL4329468 | 0.68 | TDP1 (0.39) | P2RY6MIFRAD1PNMTHSD17B10 | |
| SCHEMBL14102094 | 0.68 | GABRA1 (0.52) | P2RY6MIFALDH1A1CYP3A4HPGD | |
| Bitoscanate SCHEMBL11598436 | 0.67 | MIF (0.68) | P2RY6MIFRAD1PNMTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116417-A1 | Thiohydantoins and use thereof for treating diabetes | LABORATOIRES FOURNIER SA (FR) | 2004-06-17 | — | — | US | disclosed |