Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 13/20 | 0.41 |
| ▸ | BCHE | P06276 | 12/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419371 | 0.98 | ACHE (0.42) | ACHEBCHEKDM4EMEN1USP2 | |
| Hydrochloric Acid SCHEMBL6704055 | 0.96 | ACHE (0.43) | ACHEBCHE | |
| SCHEMBL10420306 | 0.69 | ACHE (0.47) | ACHEBCHE | |
| SCHEMBL2058677 | 0.69 | ACHE (0.47) | ACHEBCHE | |
| SCHEMBL250421 | 0.68 | ACHE (0.69) | ACHEBCHE | |
| Bromide SCHEMBL6704511 | 0.68 | ACHE (0.68) | ACHEBCHE | |
| Bromide SCHEMBL1415219 | 0.67 | ACHE (0.72) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL2578272 | 0.67 | ACHE (0.72) | ACHEBCHE | |
| Iodide SCHEMBL3434358 | 0.67 | ACHE (0.67) | ACHEBCHE | |
| SCHEMBL7046862 | 0.66 | ACHE (0.44) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004077954-A1 | ANTIMICROBIAL SOLUTION AND PROCESS | BYOCOAT ENTERPRISES, INC., (US) | 2004-09-16 | — | — | WO | disclosed |